Evaluation of argyrophilic nucleolar organiser regions (AgNORs) in multiple myeloma

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Evaluation of argyrophilic nucleolar organiser regions (AgNORs) in multiple myeloma.

AIM To investigate the prognostic value of argyrophylic nucleolar organiser regions (AgNORs) in multiple myeloma. METHODS Bone marrow aspirates from 55 newly diagnosed patients with multiple myeloma were stained with the one step AgNO3 technique. The mean number of AgNORs in each plasma cell nucleus (AgNOR count) was tested for a possible correlation with other clinical and laboratory variabl...

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Interphase argyrophilic nucleolar organiser regions and nucleolar counts in transitional cell bladder tumours.

AIMS To see whether a correlation exists between clinicopathological parameters, argyrophilic nucleolar organiser regions (AgNORs), and nucleolar counts in the nuclei of tumour cells in patients with transitional cell bladder carcinoma. METHODS Paraffin wax embedded sections from a total of 62 cases of primary transitional cell bladder carcinoma were stained with the silver colloid method. Th...

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Nucleolar organiser regions in pathology.

Traditional approaches to pathological diagnosis include macroscopic examination and formalin fixation with the preparation of paraffin sections stained with a variety of histochemical techniques. These routine approaches however may be disappointing in the assessment of many conditions and occasionally fail to render a precise diagnosis or provide adequate prognostic information. Consequently ...

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Nucleolar organiser regions (AgNORS) in anal intraepithelial neoplasia and invasive anal

Aim: To evaluate the usefulness of counting nucleolar organiser region associated proteins (AgNORs) in the management of anal squamous neoplasia. Method: Using a silver staining technique for NOR associated proteins, 32 routinely processed paraffin wax embedded sections of anal epithelium were assessed. These consisted of normal anal epithelium (n = 9), anal intraepithelial neoplasia (AIN) grad...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 2000

ISSN: 0021-9746

DOI: 10.1136/jcp.53.6.462